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Voxeleron has now released three Optical Coherence Tomography (OCT) analysis applications, each of which incorporates absolute state-of the-art computer vision and machine learning algorithms, resulting in the most advanced OCT analysis software currently available.  All are available for research purposes only and may not be used clinically.

Two of these released applications are for animal OCT and are non-exclusively licensed to Phoenix Research Labs, leaders in animal imaging.  These are InSight and InSight 3d, respectively.

The third is Orion™, our flagship product, which offers device-independent OCT image analysis software.  Orion™ is compatible with all the major OCT devices, and offers far superior analysis software and review tools than those available and shipped with the devices themselves.  Contact us today if you are interested in finding out more.

InSight 2d

The InSight application is software developed for use with Phoenix Research Labs (PRL) Image-Guided Tomography OCT systems.  It is solely for the analysis of retinal OCT images taken for animal studies.  These images are 2-d slices, or tomograms, through a retinal volume of interest.  Being made up of differing neuronal layers, the core aspect of the analysis is retinal layer thickness measurements.  With this in mind, the InSight software allows the user to:

  • Automatically segment between 2 and 4 retinal layers.
  • Edit / Delete / Add layers.

Up to 10 layers are may be analyzed.  Various reports and images may be created based on the analysis:

  • Excel spreadsheets given all layer positions and thicknesses.
  • Images showing the segmented layers overlaid on the original data.
  • Thickness plots or maps.
  • Intensity profiles through the retinal layers.

Example InSight 2d screenshot. Showing the results of image segmentation overlaid on the original image (left), the associated fundus view (top right), and a color-coded thickness map for at-a-glance interpretation of the thicknesses.

InSight 3d

InSight 3d extends upon the 2d offering, based on the better imaging capabilities offered by PRL.  As well as being able to automatically segment retinal layers, the fully 3d functionality allows this do be done over entire volumes, in seconds, thereby creating surfaces and thickness maps.  Layer volume can be analyzed and exported.  Additionally, to cope with the much larger data sets, InSight 3d also offers:

  • 3dEdit™ – the ability to edit existing and add new surfaces covering the entire volume in an intelligent way.  This drastically reduces the laborious task of editing layers in volumes and is patent pending technology.
  • 3d Visualization – the ability to render volumes and their segmentations offering a unique and informative way of assessing the data in all its glory.

Example InSight 3d automated segmentation showing cross-sectional views, rendered surfaces and thickness map.

Orion™

Voxeleron’s Orion is state-of-the-art, award-winning optical coherence tomography (OCT) research software.  Orion is fully automated, rapidly and accurately segmenting up to eight retinal layers in OCT images.

The limited functionality and poor performance of existing OCT analysis tools has meant that only two or three retinal layers are analyzed, very slowly, and often erroneously.  Comparison of results across different scanners is impossible, and functionality such as visualization, annotations and layer editing are rudimentary at best.

Orion addresses all of these technology gaps, providing clinical researchers with exactly the analysis tools they need.  Being device-independent, Orion processes data from all the main OCT vendors, paving the way for multi-center trials involving biomarkers used in the detection and management of both ocular and neurological diseases.  More details can be found on our Orion product page, here.

Example Orion screenshot showing automated segmentation of severe ocular pathology. Here the fluid volume is accurately delineated using an RPE-Baseline segmentation.

 

 

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